Studies on responsiveness of hepatoma cells to catecholamines. II. Comparison of .BETA.-adrenergic responsiveness of rat ascites hepatoma cells with cultured normal rat liver cells.
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چکیده
منابع مشابه
Regulation of insulin responsiveness in rat hepatoma cells.
Received November 28,1979 Summary: Insulin causes a 5 to lo-fold increase in the velocity of a-aminoisobutyric acid transport and a 2 to 3-fold increase in tyrosine aminotransferase activity in dexamethasone-treated hepatoma tissue culture cells. Maximal responses occur 2-4 hours after insulin addition but then decrease to control levels by 24 hours incubation. Medium conditioned by cells incub...
متن کاملproten tyrosine phosphatase activity in rat ascites hepatoma cells
protein tyrosine phosphatases (ptpases) regulate tyrosine phosphorylation of target proteins involved in several aspects of cellular functions. enzyme activities of the ptpases in cytosolic and particulate fractions of rat ascites hepatoma cell lines were determined and compared with those of normal rat liver. our present data revealed that although there was no neoplatic-specific alteration of...
متن کاملFactor from rat liver with antiinvasive potential on rat ascites hepatoma cells.
An acid/ethanol extract of normal rat liver, both in vitro and in vivo, inhibited the invasion by a highly invasive subpopulation of rat ascites hepatoma cells, AH 130 (LC-AH cells). The addition of 10-80 micrograms/ml extract inhibited the formation of penetrated colonies of LC-AH cells underneath the cultured mesothelial cell (M-cell) monolayer. The tumor cells pretreated with the extract sho...
متن کاملMacrophage potentiation of invasive capacity of rat ascites hepatoma cells.
In vitro and in vivo invasive capacities of rat ascites hepatoma cells (AH 130) that had been cultured on the feeder layers of rat macrophages were examined. The in vitro invasive capacity of the tumor cells was measured by their ability to form tumor cell colonies underneath cultured mesothelial cell monolayers; in vivo invasive capacity was examined by the implantation of the tumor cells into...
متن کاملPutrescine-dependent invasive capacity of rat ascites hepatoma cells.
The effects of inhibitors of polyamine synthesis on the invasive capacity of rat ascites hepatoma (LC-AH) cells were examined by in vitro assay of penetration of the LC-AH cells through a monolayer of calf pulmonary arterial endothelial (CPAE) cells. Pretreatment of LC-AH cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, before seeding them onto a CPAE ce...
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ژورنال
عنوان ژورنال: The Japanese Journal of Pharmacology
سال: 1985
ISSN: 0021-5198,1347-3506
DOI: 10.1254/jjp.38.101